From The Legume Laboratory

Using cucumber mosaic virus (CMV) and tobacco mosaic virus (TMV) as the two RNA viruses to be targeted, the researchers took the Cas9 protein from Francisella novicida (FnCas9) and used it in combination with guide RNAs directed toward a variety of targets within the CMV and TMV genomes, then assessed whether the construct had any effect of infection rates and severity compared to control plants. This blog discusses the article in more detail.