The most significant contribution Dr. Argelia Lorence has made to plant sciences has been the discovery of a novel biosynthetic pathway for vitamin C that involves myo-inositol as a main precursor. Her laboratory uses Arabidopsis to better understand the role of various subcellular pools of vitamin C in plant physiology. Her ongoing research has potential applications for the development of crop plants with enhanced nutritional content, better growth, and improved tolerance to multiple environmental stresses. In addition to Arabidopsis, her current models of study include rice, soybean, tobacco and maize.

Dr. Lorence directs the high throughput plant phenotyping facility at A-State. She co-directed the Plant Imaging Consortium, PIC, a multi-state effort that uses phenomics and other imaging techniques to allow researchers to adapt crops to meet the challenges of a changing climate and a growing world population. She is also co-principal investigator of the Wheat and Rice Center for Heat Resilience, project focused on finding novel genes involved in conferring rice and wheat tolerance to high night temperature, one of the key factors limiting the yields of the two most important crops in the world for food security.

Since joining A-State in 2005, Dr. Lorence has secured over $18 million in grants from the National Science Foundation, the National Institutes of Health, and the U.S. Department of Agriculture. Her accolades include the Arthur Neish Young Investigator Award from the Phytochemical Society of North America (PSNA), Featured Mentor from the Minority Environmental Leadership Development Initiative, Distinguished Woman in Science by the Congress of the State of Morelos, and the Outstanding Hispanic Achiever of the Year Award from Hispanic Community Services in Jonesboro. She received an Endowed Professorship for her contributions to research and teaching at A-State in 2017.

Prior to joining A-State, Dr. Lorence was a post-doctoral research associate at Texas A&M and at Virginia Tech. Dr. Lorence received a doctorate in 1997 and a master’s degree in biotechnology in 1995 from the National Autonomous University of Mexico (UNAM). She earned a bachelor’s degree in biochemical engineering from Autonomous Metropolitan University (UAM) in 1991.  

Research Areas:
Biochemistry, Molecular Biology, Phenomics, Abiotic Interactions


  • Gehan MA, Fahlgren N, Abbasi A, Berry JC, Callen ST, Chavez  L, Doust A, Feldman M, Gilbert K, Hodge J, Hoyer JS, Lin A, Liu S*, Lizarraga C, Lorence A, Miller M, Platon E, Tessman M, Sax T (2017) PlantCV v2.0: Image Analysis Software for High-Throughput Plant Phenotyping. PeerJ 5:e4088; doi 10.7717/peerj.4088.

  • Liu S* Acosta-Gamboa L*, Huang X, Lorence A (2017) Novel low cost 3D surface model reconstruction system for plant phenotyping. Journal of Imaging 3, 39, doi:10.3390/ jimaging3030039.

  • Aboobucker SI*, Suza WP*, Lorence A (2017) Characterization of two Arabidopsis L-gulono-1,4-lactone oxidases, AtGulLO3 and AtGulLO5, involved in ascorbate biosynthesis. Reactive Oxygen Species 4(12): 1-29.

  • Hawkesford ML, Lorence A (2017). Plant phenotyping: increasing throughput and precision at multiple scales. Functional Plant Biology 44: v-vii,

  • Acosta-Gamboa LM*, Liu S*, Langley E*, Campbell Z*, Castro-Guerrero N, Mendoza-Cózatl D, Lorence A (2017). Moderate to severe water limitation differentially affects the phenome and ionome of Arabidopsis. Functional Plant Biology 44: 94-106
  • Cruz-Morales S, Castañeda-Gómez J, Rosas-Ramírez D, Fragoso-Serrano M, Figueroa-González G, Lorence A, Pereda-Miranda RG (2016) Resin glycosides from Ipomoea alba seeds as potential chemosensitizers in breast carcinoma cells. Journal of Natural Products 79(12): 3093-3104.

  • Yactayo-Chang JP*, Yoon S, Teoh KT, Hood NC, Lorence A, Hood E (2016) Failure to over-express expansin in multiple heterologous systems. New Negatives in Plant Science.

    3: 10-18.

  • Aboobucker SI*, Lorence A (2016) Recent progress on the characterization of aldonolactone oxidoreductases. Plant Physiology and Biochemistry 98: 171-185.

  • Lisko KA*, Torres R*, Harris RS*, Belisle M*, Jullian B*, Vaughan MM*, Chevone BI, Mendes P, Nessler CL, Lorence A (2013) Elevating vitamin C content via overexpression of myo-inositol oxygenase and L-gulono-1,4-lactone oxidase in Arabidopsis  leads to enhanced biomass and tolerance to abiotic stresses. In Vitro Cellular and Developmental Biology Plant. 49:643-655.

  • Avila CA, Arévalo-Solíz ML, Lorence A, Goggin FL (2013) Expression of α-DIOXYGENASE 1 in tomato and Arabidopsis contributes to plant defenses against aphids. Molecular Plant-Microbe Interactions 26(8):977-986.

  • Lisko KA*, Hubstenberger J, Phillips G, Belefant-Miller H, McClung A, Lorence A (2013). Ontogenetic changes in vitamin C in selected rice varieties. Plant Physiology and Biochemistry 66: 41-46.

  • Sharma A*, Folch-Mallol JL, Cardoso-Taketa AT, Lorence A, Villarreal ML (2012) DNA barcoding of the Mexican sedative and anxiolytic plant Galphimia glauca. Journal of Ethnopharmacology 144:371-378.

  • Cruz-Morales S, Castañeda-Gómez J, Figueroa-González G, Mendoza-García AD, Lorence A, Pereda-Miranda R (2012). Mammalian multidrug resistance lipopentasaccharide inhibitors from Ipomoea alba seeds. Journal of Natural Products 75: 1603-1611.

  • Haroldsen V, Chi-Ham CL, Kulkarni S*, Lorence A, Bennet AB (2011) Constitutively expressed DHAR and MDHAR influence fruit, but not foliar ascorbate levels in tomato. Plant Physiology and Biochemistry 49: 1244-1249.

  • Goggin FL, Avila CA, Lorence A (2010) Vitamin C content in plants is modified by insects and influence susceptibility to herbivory. BioEssays 32: 777-790.

  • Suza WP*, Avila CA, Carruthers K, S Kulkarni*, Goggin FL, Lorence A (2010) Exploring the Impact of Wounding and Jasmonates on Ascorbate Metabolism. Plant Physiology and Biochemistry 48: 337-350.

  • Mannan A, Liu C, Arsenault P, Towler MJ, Vail D, Lorence A, Weathers PJ (2010) DMSO triggers the generation of ROS leading to an increase in artemisinin and dehydroartemisinic acid in Artemisia annua shoot cultures. Plant Cell Reports, 29(2):143-152.

  • Zhang W, Lorence A, Gruszewski HA, Chevone BI, Nessler CL (2009) AMR1, an Arabidopsis gene that coordinately and negatively regulates the mannose/L-galactose ascorbic acid biosynthetic pathway. Plant Physiology 150: 942-950.

  • Dabul ANG*, Belefant-Miller HB, RoyChowdhury M, Hubstenberger JF, Lorence A, Phillips GC (2009) Screening of a broad range of rice (Oryza sativa L.) germplasm for in vitro rapid regeneration and development of an early prediction system. In Vitro Cellular and Developmental Biology Plant 44: 414-420.

  • Pereda-Miranda R, Villatoro-Vera R*, Bah M, Lorence A (2009) Pore-forming activity of morning glory resin glycosides in model membranes. Revista Latinoamericana de Química 37(2): 144-154.

  • Suza WP*, Harris RS*, Lorence A (2008) Hairy roots: From high-value metabolite production to phytoremediation. Electronic Journal of Integrative Biosciences. Published online November 21, 2008.

  • Schroeter C, House LA, Lorence A (2007) Fruits and Vegetable Consumption Among College Students in Arkansas and Florida: Food Culture vs. Health Knowledge. International Food and Agribusiness Management Review 10: 63-89.

  • Lorence A, Mendes P, Chevone BI, Nessler CL (2004) myo- Inositol Oxygenase Offers a Possible Entry Point into Plant Ascorbate Biosynthesis. Plant Physiology 134: 1200-1205.

  • Lorence A, Medina-Bolivar F, Nessler CL (2004) Camptothecin and 10-Hydroxycamptothecin from Camptotheca acuminata Hairy Roots. Plant Cell Reports 22: 437-441.

  • Lorence A and Nessler CL (2004) Camptothecin, Over Four Decades of Surprising Findings. Phytochemistry 65: 2735-2749. Review paper by invitation to section Molecules of Interest.

  • Lorence A, and Verpoorte R (2004) Gene Transfer and Expression in Plants. Methods in Molecular Biology 267: 329-350.

  • Radzio J, Lorence A, Chevone BI, Nessler CL (2003) L-Gulono-1,4-lactone Oxidase Expression Rescues Vitamin C Deficient Arabidopsis (vtc) Mutants. Plant Molecular Biology 53: 837-844.

  • Soberón M, Pérez RV, Núñez-Valdéz ME,  Lorence A, Gómez I, Sánchez J, Bravo A (2000) Evidence for Intermolecular Interaction as a Necessary step for Pore-Formation Activity and Toxicity of Bacillus thuringiensis Cry1Ab Toxin. FEMS Microbiology Letters 191: 221-225.

  • Lorence A, Darszon A, Bravo A (1997) Aminopeptidase Dependent Pore Formation of Bacillus thuringiensis Cry1Ac Toxin on Trichoplusia ni Membranes. FEBS Letters 414: 303-307.

  • Lorence A, Darszon A, Díaz C, Liévano A, Quintero R, Bravo A (1995) δ-Endotoxins Induce Cation Channels in Spodoptera frugiperda Brush Border Membrane in Suspension and in Planar Lipid Bilayers”. FEBS Letters 360: 217-222.

  • Bravo A, Lorence A, Quintero R (1995) Biopesticides Compatible with the Environment: Bacillus thuringiensis a Unique Model. Biocontrol 1: 41-55.

Volunteer Activities

Currently serving as Nova (STEM) Mentor for the Boy Scouts of America

Current Affiliations
Experience & Education