Bio

I'm a plant epigeneticist at The Sainsbury Laboratory Cambridge University. After completing my Master Degree in Genetics, Development and Cellular Biology, I obtained my PhD thesis describing the role of histone variants and chaperones on chromatin dynamics during Arabidopsis development (Clermont Auvergne University - France). I'm currently a post-doctoral Research Associate in Jerzy Paszkowski's lab in The Sainsbury Laboratory at the University of Cambridge. My research focuses on the developmental, environmental and epigenetic regulation of tomato retrotransposons. My main interests are in fruit development and ripening, and in plants subjected to abiotic stress, particularly drought. I am also working to establish and characterize plants deficient in DNA methylation and in chromatin remodellers and modifiers that are likely to interfere with retrotransposon control.

Research Areas:
Gene Regulation, Genetics, Genomics, Molecular Biology

Publications

Benoit M, Simon L, Desset S, Duc C, Cotterell S, Poulet A, Le Goff S, Tatout C, Probst A V. (2018) Replication-coupled histone H3.1 deposition determines nucleosome composition and heterochromatin dynamics during Arabidopsis seedling development. New Phytol.

Duc C, Benoit M, Détourné G, Simon L, Poulet A, Jung M, Veluchamy A, Latrasse D, Le Goff S, Cotterell S, et al. (2017) Arabidopsis ATRX Modulates H3.3 Occupancy and Fine-Tunes Gene Expression. Plant Cell 29: 1773–1793.

Poulet A, Duc C, Voisin M, Desset S, Tutois S, Vanrobays E, Benoit M, Evans DE, Probst A V., Tatout C (2017) The LINC complex contributes to heterochromatin organisation and transcriptional gene silencing in plants. J Cell Sci 130: 590–601.

Duc C, Benoit M, Le Goff S, Simon L, Poulet A, Cotterell S, Tatout C, Probst A V. (2015) The histone chaperone complex HIR maintains nucleosome occupancy and counterbalances impaired histone deposition in CAF-1 complex mutants. Plant J 81: 707–722.

Benoit M, Layat E, Tourmente S, Probst A V. (2013) Heterochromatin dynamics during developmental transitions in Arabidopsis — a focus on ribosomal DNA loci. Gene 526: 39–45.

Volunteer Activities

Organisation of the 15th Doctoral School for Life Sciences, Health, Agronomy and Environment Days (May 2012): a 3 days event allowing PhD students of the university to present their work to the fellow students, University Clermont-Auvergne

Cambridge Science Festival (March 2016): activity on plant mutants available at the supermarket, focus on tomato, The Sainsbury Laboratory Cambridge

Festival of Plant (May 2016): ambassador at the Pop Up Science Tent, Cambridge University Botanic Garden

Career in Plants Day (July 2016): Speed Dating Activity on Careers in Plant Sciences, The Sainsbury Laboratory Cambridge

Cambridge University’s Realise programme for children in care (August 2016): Animation of a workshop dedicated to Plant Genetics, The Sainsbury Laboratory Cambridge

Scientific Discovery Trail by Gatsby Plant Science Education program (August 2016): Animation of a workshop dedicated to mutations and what they mean in plants, The Sainsbury Laboratory Cambridge

Big Biology Day (October 2016):  celebrating the life sciences and engaging the general public with an array of biological topics - activities on plant trichome mutants, Hills Road Sixth Form College Cambridge

Cambridge Science Festival (March 2017): Plant Science Pop Up Tent, Downing Site, Department of Plant Sciences Cambridge

Interests
Current Affiliations
Experience & Education