Bio

I am a plant molecular geneticist with over 17 years’ experience in various fields of plant science. I have worked in academia, the DOE national laboratory system and in the biotech industry. I currently lead the development of regulatory strategies for early Bayer Crop Science pipeline products in both the insect control platform and genome editing.

Research Areas:
Applied Plant Biology, Molecular Biology

Publications

1. Lin, F., Manisseri, C., Fagerstrom, A., Peck, M. L., Vega-Sanchez, M. E., Williams, B., Chiniquy, D.M., Saha, P., Pattahil, S., Conlin, B., Zhu, L., Hahn, M. G., Willats, W. G. T., Scheller, H. V., Ronald, P. C., Bartley, L. E. 2016. Cell wall composition and candidate biosynthesis gene expression across rice development. Plant and Cell Physiology 57:2058-2075.

 

2. Li, G., Chern, M., Jain, R., Martin, J. A., Schackwitz, W. S., Jian, L., Vega-Sanchez, M. E., Lipzen, A. M., Barry, K. W., Schmutz, J., Ronald, P. C. 2016. Genome-wide sequencing of 41 rice (Oryza sativa) mutated lines reveals diverse mutations induced by fast-neutron irradiation. Molecular Plant 9:1078-1081.

 

3. Costa, T. H., Vega-Sanchez, M. E., Milagres, A. M. F., Scheller, H. V., Ferraz, A. 2016. Tissue-specific distribution of hemicelluloses in six different sugarcane hybrids as related to cell wall recalcitrance. Biotechnology for Biofuels 9:99.

 

4.Sun, L., Singh, S., Joo, M., Vega-Sánchez, M., Ronald, P., Simmons, B. A., Adams, P., Auer, M. 2016. Non-invasive imaging of cellulose microfibril orientation within plant cell walls by polarized Raman microspectroscopy. Biotechnology and Bioengineering 113:82-90.

 

5.  Smith-Moritz, A. M., Hao, Z., Fernández-Niño, S.G., Fangel, J. U., Verhertbruggen, Y., Holman, H. Y. N., Willatts, W. G. T., Ronald, P. C., Scheller, H. V., Heazlewood, J. L., Vega-Sánchez, M. E*. 2015. Structural characterization of a mixed-linkage glucan deficient mutant reveals alteration in cellulose microfibril orientation in rice coleoptile mesophyll cell walls. Frontiers in Plant Science 6:628.

*Corresponding author

 

6. Vega-Sánchez, M. E., Loqué, D., Lao, J., Catena, M., Verhertbruggen, Y., Herter, T., Yang, F., Harholt, J., Ebert, B., Baidoo, E. E. K., Keasling, J. D., Scheller, H. V., Heazlewood, J. L., Ronald, P. C. 2015. Engineering temporal accumulation of a low recalcitrance polysaccharide leads to increased C6 sugar content in plant cell walls. Plant Biotechnology Journal 13:903-914.

 

7. Tanger, P., Vega-Sánchez, M. E., Fleming, M., Tran, L., Singh, S., Abrahamson, J. B., Jahn, C. E., Santoro, N., Naredo, E. B., Baraoidan, M., Danku, J. M. C., Salt, D. E., McNally, K. L., Simmons, B. A., Ronald, P. C., Leung, H., Bush, D. R., McKay, J. K., Leach, J. E. 2015. Cell wall composition and bioenergy potential of rice straw tissues are influenced by environment, tissue type and genotype. BioEnergy Resesarch 8:1165-1182.

 

8. Lao, J., Oikawa, A., Bromley, J. R., McInerney, P., Suttangkakul, A., Smith-Moritz, A. M., Plahar, H., Chiu, TY., González Fernández-Niño, S. M., Ebert, B., Yang, F., Christiansen, K. M., Hansen, S. F., Stonebloom, S., Adams, P. D., Ronald, P. C., Hillson, N. J., Hadi, M. Z., Vega-Sánchez, M. E., Loqué, D., Scheller, H. V., Heazlewood, J. L. 2014. The plant glycosyltransferase clone collection for functional genomics. Plant Journal 79:517-529.

 

9. Shirsekar, G.S.*, Vega-Sánchez, M.E.*, Bordeos, A., Baraoidan, M., Swisshelm, A., Fan, J., Park, C.H., Leung, H., Wang, G.L. 2014. Identification and characterization of suppressor mutants of spl11-mediated cell death in rice. Molecular Plant-Microbe Interactions 27:528-536.

*Equal contribution

 

10. Cai, Y., Vega-Sánchez, M.E., Park, C.H., Bellizzi, M., Guo, Z., Wang, G.L. 2014. RBS1, an RNA Binding Protein, Interacts with SPIN1 and is Involved in Flowering Time Control in Rice. PLoS One 9 (1): 87258.

 

11. Ito, J., Herter, T., Baidoo, E., Lao, J., Vega-Sánchez, M.E., Smith-Moritz, A. M., Adams, P.D., Keasling, J.D., Usadel, B., Petzold, C.J., Heazlewood J.L. 2014. Analysis of plant nucleotide sugars by hydrophilic interaction liquid chromatography and tandem mass spectrometry. Analytical Biochemistry 448:14-22.

 

12. Bartley, L.E., Peck, M.L., Kim, S.R., Ebert, E., Manisseri, C., Chiniquy, D.M., Sykes, R., Gao, L., Rautengarten, C., Vega-Sánchez, M.E., Benke, P.I., Canlas, P.E., Cao, P., Brewer, S., Lin, F., Smith, W.L., Zhang, X., Keasling, J.D., Jentoff, R.E., Foster, S.B., Zhou, J., Ziebell, A., An, G., Scheller, H.V., Ronald, P.C. 2013. Overexpression of a BAHD Acyltransferase, OsAt10, alters rice cell wall hydroxycinnamic acid content and saccharification. Plant Physiology 161: 1615-1633.

 

13. Vega-Sánchez, M. E., Verhertbruggen, Y., Scheller, H. V., Ronald, P. C. 2013. Abundance of mixed linkage glucan in mature tissues and secondary cell walls of grasses. Plant Signaling and Behavior 8:2, e23143.

 

14. Chen, X., Vega-Sánchez, M. E., Verhertbruggen, Y., Chiniquy, D., Canlas, P. E., Fagerstrom, A., Prak, L., Christensen, U., Oikawa, A., Chern, M., Zuo, S., Lin, F., Auer, M., Willats, W. G. T., Bartley, L., Harholt, J., Scheller, H. V., Ronald, P. C. 2013. Inactivation of OsIRX10 leads to decreased xylan content in rice culm cell walls and improved biomass saccharification. Molecular Plant 6:570-573.

 

15. Varanasi, P., Katsnelson, J., Larson, D. M., Sharma, R., Sharma, M. K., Vega-Sánchez, M. E., Zemla, M., Loque, D., Ronald, P. C., Simmons, B. A., Singh, S., Adams, P. D., Auer, M. 2012. Mechanical stress analysis as a method to understand the impact of genetically engineered rice and Arabidopsis plants. Industrial Biotechnology 8:238-244.

 

16. Vega-Sánchez, M. E., Verhertbruggen, Y., Christensen, U., Chen, X., Sharma, V., Varanasi, P., Jobling, S. A., Talbot, M., White, R. G., Joo, M., Singh, S., Auer, M., Scheller, H. V., Ronald, P. C.  2012. Loss of Cellulose Synthase-Like F6 function affects mixed-linkage glucan deposition, cell wall mechanical properties and defense responses in vegetative tissues of rice. Plant Physiology 159:56-69.

 

17. Smith-Moritz, A. M., Chern, M., Lao, J., Sze-To, W. H., Heazlewood, J. L., Ronald, P. C., Vega-Sánchez, M. E*.  2011.  Combining multivariate analysis and monosaccharide composition modeling to identify plant cell wall variations by Fourier Transform Near Infrared spectroscopy.  Plant Methods 7:26. *Corresponding author

 

18. Bart, R. S., Chern, M., Vega-Sánchez, M. E., Canlas, P., Ronald, P. C.  2010.  Rice Snl6, a Cinnamoyl CoA Reductase-like gene family member, is required for NH1-mediated immunity to Xanthomonas oryzae pv. oryzaePLoS Genetics 6 (9):  e1001123.

 

19. Vega-Sánchez, M. E., Ronald, P. C.  2010.  Genetic and biotechnological approaches for biofuel crop improvement.  Current Opinion in Biotechnology 21:218-224.

 

20. The International Brachypodium Initiative.  2010.  Genome sequencing and analysis of the model grass Brachypodium distachyonNature 463:763-768.

 

21. Vega-Sánchez, M. E., Zeng, L.-R., Chen, S., Leung, H., Wang, G-.L.  2008.  SPIN1, a K homology domain protein negatively regulated and ubiquitinated by the E3 ubiquitin ligase SPL11, is involved in flowering time control in rice.  Plant Cell 20:1456-1469.

 

22. Vega-Sánchez, M. E., Gowda, M., Wang, G-. L.  2007.  Tag-based approaches for deep transcriptome analysis in plants.  Plant Science 173:371-380.

 

23. Chen, S., Tao, L., Zeng, L.-R., Vega-Sánchez, M. E., Umemura, K.,Wang, G.-L.  2006.  A highly efficient transient protoplast system for analyzing defence gene expression and protein-protein interactions in rice. Molecular Plant Pathology 7:417-427.

 

24. Zeng, L.-R., Vega-Sánchez, M. E., Zhu, T., Wang, G.-L.  2006.  Ubiquitination-mediated protein degradation and modification:  an emerging theme in plant-microbe interactions. Cell Research 16:413-426.

 

25. Vega-Sánchez, M.E., Redinbaugh, M. G., Costanzo, S., Dorrance, A. E.  2005.  Spatial and temporal expression analysis of defense-related genes in soybean cultivars with different levels of partial resistance to Phytophthora sojaePhysiological and Molecular Plant Pathology 66:175-182.

 

26. Vega-Sánchez, M.E., Erselius, L. J., Rodriguez, A. M., Bastidas, O., Hohl, H. R., Ojiambo, P. S., Mukalazi, J., Vermeulen, T., Fry, W. E., Forbes, G. A.  2000.  Host adaptation to potato and tomato within the US-1 clonal lineage of Phytophthora infestans in Uganda and Kenya.  Plant Pathology 49:531-539.

 

27. Erselius, L. J., Vega-Sánchez, M.E., Forbes, G. A.  2000.  Stability in population of Phytophthora infestans attacking tomato in Ecuador demonstrated by cellulose-acetate assessment of Glucose-6-Phosphate Isomerase.  Plant Disease 84:325-327.

Volunteer Activities

ASPB Minority Affairs Committee member

Interests
Current Affiliations
Experience & Education