I'm a Group Leader interested in the functions of proteolytic pathways during plant immunity. 

Career Status:
Faculty/Group Leader, Major Research University: Pre-Tenure

Research Areas:
Biochemistry, Biotic Interactions, Cell Biology, Molecular Biology


1. Üstün S., Hafrén A., Liu Q., Marshall R., Minina E.A., Bozhkov P., Vierstra R., Hofius D. (2018) Bacteria exploit autophagy for proteasome degradation and enhanced virulence in plants. Plant Cell, accepted

2. Hafrén A., Üstün S., Hochmuth A., Svenning S., Johansen T., Hofius D. (2017) Turnip mosaic virus counteracts NBR1-mediated selective autophagy of the 
viral silencing suppressor HCpro. Plant Physiology pp.01198.2017; DOI: 10.1104/pp.17.01198

3. Üstün S., Hafrén A., Hofius D. (2017). Autophagy as a mediator of life and death in plants. Curr Opin Plant Biol 40, 122-130.

4. Üstün, S.* and Börnke, F. (2017). Ubiquitin Proteasome Activity Measurement in Total Plant Extracts. Bio-protocol 7(17): e2532. DOI: 10.21769/BioProtoc.2532.

5. Witzel, K.; Üstün, S.; Schreiner, M.; Grosch, R.; Börnke, F.; Ruppel, S. (2017) A proteomic approach suggests unbalanced proteasome functioning induced by the growth-promoting bacterium Kosakonia radicincitans in Arabidopsis. Frontiers in Plant Science. 2017 8:661.

6. Üstün S.*, Sheikh A., Gimenez-Ibanez S., Jones A., Ntoukakis V., Börnke F. (2016) The proteasome acts as a hub for plant immunity and is targeted by Pseudomonas type-III effectors. Plant Physiology 172: 1941-1958

7. Üstün S., Bartetzko V., Börnke F. (2015) The Xanthomonas effector XopJ triggers a conditional hypersensitive response upon treatment of N. benthamiana leaves with salicylic acid. Frontiers Plant Science 6:599

8. Üstün S.* and Börnke F (2015) The Xanthomonas campestris type III effector XopJ proteolytically degrades proteasome subunit RPT6. Plant Physiology 168: 107-119

9. Üstün S.* and Börnke F (2014) Interactions of Xanthomonas type-III effector proteins with the plant ubiquitin and ubiquitin-like pathways. Frontiers Plant Science 5:736

10. Üstün S.*, König P., Guttman D.S., Börnke F. (2014) HopZ4 from Pseudomonas syringae, a novel member of the HopZ type III effector family from the YopJ superfamily, inhibits the proteasome in plants. Molecular Plant-Microbe Interaction 27: 611-623

11. Üstün S., Bartetzko V., Börnke F. (2013) The Xanthomonas campestris Type III Effector XopJ Targets the Host Cell Proteasome to Suppress Salicylic-Acid Mediated Plant Defence. PLoS Pathogens 9: e1003427

12. Üstün, S., Müller, P., Palmisano, R., Hensel, M., Börnke, F. (2012). SseF, a type III effector protein from the mammalian pathogen Salmonella enterica, requires resistance-gene-mediated signalling to activate cell death in the model plant Nicotiana benthamiana. New Phytologist 194: 1046-1060.

13. Arsova, B., Hoja, U., Wimmelbacher, M., Greiner, E., Üstün, S., Melzer, M., Petersen, K., Lein, W., Börnke, F. (2010). Plastidial Thioredoxin z Interacts with two Fructokinase-like Proteins in a Thiol-Dependent Manner: Evidence for an essential Role in Chloroplast Development in Arabidopsis and Nicotiana benthamianaPlant Cell 22: 1498-1515.

Current Affiliations
Experience & Education