Irakli Loladze is a Mathematical Biologist. He is a graduate of Vekua Physics-Mathematical School #42 and Tbilisi State University. He obtained his MA and PhD degrees in mathematics at Arizona State University. He then worked as a postdoc at Princeton University, where in 2002 he postulated that rising atmospheric carbon dioxide levels (CO2) decrease the concentrations of minerals essential for human nutrition, including iron and zinc, in plants globally. After years of compiling data, in 2014 he published a meta-analysis revealing a pervasive and systemic downshift in mineral levels in plants worldwide. His research came to influence US policy and was highlighted by New Scientist, Nature, Science, and in a two--times award winning article in Politico. This year, Loladze and collaborators showed that rising CO2 levels result in lower levels of plant carotenoids critical for human eye and brain health.
Career Status: Faculty/Group Leader, Major Research University: Post-Tenure
Research Areas: Environmental Plant Biology, Food Security, Ecology, Biochemistry, Physiology
LEAD-AUTHOR PEER-REVIEWED PUBLICATIONS
Loladze, I., Nolan, J. , Ziska, L.W., Knobbe, A. (2019) Rising atmospheric CO2 lowers concentrations of plant carotenoids essential to human health: Meta-analysis. Molecular nutrition & food research, 1801047 DOI:10.1002/mnfr.201801047 PDF
Loladze, I. (2019) Iterative chemostat: A modelling framework linking biosynthesis to nutrient cycling on ecological and evolutionary time scales. Mathematical Biosciences and Engineering, 16(2): 990-1004. doi: 10.3934/mbe.2019046, PDF
Loladze, I., Nolan, J. M., Ziska, L., & Knobbe, A. (2018). Rising atmospheric CO2 tends to lower carotenoid levels in plants: Can the global decline in dietary carotenoids affect human vision and memory? J of Alzheimer's Disease (Vol. 64, pp. 1042–1042). Ios Press Nieuwe Hemweg 6B, 1013 Bg Amsterdam, Netherlands.
Loladze, I. (2014) "Hidden shift of the ionome of plants exposed to elevated CO2 depletes minerals at the base of human nutrition" eLife doi:10.7554/eLife.02245 (F1000 Primary rating: Exceptional: Körner C: F1000Prime Recommendation of [Loladze I, elife 2014 3:e02245]. In F1000Prime, 31 Jul 2014; doi: 10.3410/f.718432028.793497713,
Loladze, I. and Elser J.J. (2011) The origins of the Redfield nitrogen-to-phosphorus ratio are in a homoeostatic protein-to-rRNA ratio, Ecology Letters, 14, 244-250 (Editor’s Choice, Science) (PDF)
Loladze, I., Kuang, Y., Elser, J.J. & Fagan, W.F. (2004) Competition and Stoichiometry: Coexistence of two predators on one prey. Theoretical Population Biology 65: 1-15
Loladze, I. (2002) Rising CO2 and human nutrition: toward globally imbalanced plant stoichiometry? Trends in Ecology and Evolution, 17, 457-461 (highlighted in Nature, covered by New Scientist)
Loladze, I., Kuang, Y. Elser, J.J. (2000) Stoichiometry in producer-grazer systems: linking energy flow with element cycling, Bulletin of Mathematical Biology 62, 1137-1162
Most of my CO2-related research was done on volunteer bases with zero funding.