Bio

Dr. Tello-Ruiz has served as the Project Manager and Lead Outreach Coordinator for the Gramene Database since 2012. She graduated from SUNY Stony Brook, and trained in population genetics at the Broad Institute of Harvard University and MIT. She has 10 years of experience in bioinformatics at CSHL. She holds a bachelor's degree in Biochemical Engineering from the Instituto Tecnológico y de Estudios Superiores de Monterrey. She also served as the project manager for the Human HapMap Coordinating Center, and coordinated international collaborative efforts with the Type 2 Diabetes Chromosome 1q Consortium and Beta-Cell Therapy Group to sculpt, curate, and integrate diabetes pathways into the Reactome Pathways Database. She taught for 1.5 years at the undergraduate level at SUNY Stony Brook and the Polytechnical Institute of New York University.

Research Areas:
Genetics, Genomics, Computational Biology, Education and Outreach

Publications

Book chapters

  • Tello-Ruiz MK, Stein J, Wei S, Youens-Clark K, Jaiswal P, Ware D (2016). "Gramene: A Resource for Comparative Analysis of Plants Genomes and Pathways". Plant Bioinformatics: Methods and Protocols. David Edwards (ed). 2nd edition. Springer New York. Methods Mol Biol. 1374:141-63. doi: 10.1007/978-1-4939-3167-5_7
  • Tello-Ruiz MK, Walsh EC, Rioux JD. 2006. "Gastro-enterologic and hepatic diseases". Immunogenetics of Autoimmune Disease. J Oksenberg and D Brassat (eds). Landes Biosciences and Springer Verlag. ISBN: 978-0-387-36004-1

Peer-reviewed articles

  1. Tello-Ruiz MK, Naithani S, Stein JC, Gupta P, Campbell M, Olson A, Wei S, Preece J, Geniza MJ, Jiao Y, Lee YK, Wang B, Mulvaney J, Chougule K, Elser J, Al-Bader N, Kumari S, Thomason J, Kumar V, Bolser DM, Naamati G, Tapanari E, Fonseca N, Huerta L, Iqbal H, Keays M, Munoz-Pomer Fuentes A, Tang A, Fabregat A, D'Eustachio P, Weiser J, Stein LD, Petryszak R, Papatheodorou I, Kersey PJ, Lockhart P, Taylor C, Jaiswal P, Ware D. 2018. Gramene 2018: unifying comparative genomics and pathway resources for plant research. Nucleic Acids Res. 46(D1):D1181-D1189.
  2. Kersey PJ, Allen JE, Allot A, Barba M, Boddu S, Bolt BJ, Carvalho-Silva D, Christensen M, Davis P, Grabmueller C, Kumar N, Liu Z, Maurel T, Moore B, McDowall MD, Maheswari U, Naamati G, Newman V, Ong CK, Paulini M, Pedro H, Perry E, Russell M, Sparrow H, Tapanari E, Taylor K, Vullo A, Williams G, Zadissia A, Olson A, Stein J, Wei S, Tello-Ruiz M, Ware D, Luciani A, Potter S, Finn RD, Urban M, Hammond-Kosack KE, Bolser DM, De Silva N, Howe KL, Langridge N, Maslen G, Staines DM, Yates A. 2018. Ensembl Genomes 2018: an integrated omics infrastructure for non-vertebrate species. Nucleic Acids Res. 46(D1):D802-D808.
  3. Tello-Ruiz MK, Stein J, Wei S, Preece J, Olson A, Naithani S, Amarasinghe V, Dharmawardhana P, Jiao Y, Mulvaney J, Kumari S, Chougule K, Elser J, Wang B, Thomason J, Bolser DM, Kerhornou A, Walts B, Fonseca NA, Huerta L, Keays M, Tang YA, Parkinson H, Fabregat A, McKay S, Weiser J, D'Eustachio P, Stein L, Petryszak R, Kersey PJ, Jaiswal P, Ware D. 2016. Gramene 2016: comparative plant genomics and pathway resources. Nucleic Acids Res. 44(D1):D1133-40.
  4. Kersey PJ, Allen JE, Armean I, Boddu S, Bolt BJ, Carvalho-Silva D, Christensen M, Davis P, Falin LJ, Grabmueller C, Humphrey J, Kerhornou A, Khobova J, Aranganathan NK, Langridge N, Lowy E, McDowall MD, Maheswari U, Nuhn M, Ong CK, Overduin B, Paulini M, Pedro H, Perry E, Spudich G, Tapanari E, Walts B, Williams G, Tello-Ruiz M, Stein J, Wei S, Ware D, Bolser DM, Howe KL, Kulesha E, Lawson D, Maslen G, Staines DM. 2016. Ensembl Genomes 2016: more genomes, more complexity. Nucleic Acids Res. 44(D1):D574-80.
  5. Tello-Ruiz MK*, Gupta P*, Naithani S*, Chougule K, D’Eustachio P, Fabregat A, Jiao Y, Keays M, Lee YK, Kumari S, Mulvaney J, Olson A, Preece J, Stein J, Wei S, Weiser J, Huerta L, Petryszak R, Kersey P, Stein LD, Ware D, Jaiswal P. 2016. Gramene Database: Navigating Plant Comparative Genomics Resources. Current Plant Biology, 7-8. pp. 10-15. ISSN 2214-6628. [* = equal contribution]
  6. Monaco MK, Stein J, Naithani S, Wei S, Dharmawardhana P, Kumari S, Amarasinghe V, Youens-Clark K, Thomason J, Preece J, Pasternak S, Olson A, Jiao Y, Lu Z, Bolser D, Kerhornou A, Staines D, Walts B, Wu G, D’Eustachio P, Haw R, Croft D, Kersey PJ, Stein L, Jaiswal P, Ware D. 2014. Gramene 2013: comparative plant genomics resources. Nucl. Acids Res. 42 (D1): D1193-D1199.
  7. Kersey PJ, Allen JE, Christensen M, Davis P, Falin LJ, Grabmueller C, Hughes DST, Humphrey J, Kerhornou A, Khobova J, Langridge N, McDowall MD, Maheswari U, Maslen G, Nuhn M, Ong CK, Paulini M, Pedro H, Toneva I, Tuli MA, Walts B, Williams G, Wilson D, Youens-Clark K, Monaco MK, Stein J, Wei X, Ware D, Bolser D, Howe K, Kulesha E, Lawson D, Staines DM. 2014. Ensembl Genomes 2013: scaling up access to genome-wide data. Nucl. Acids Res. 42 (D1): D546-D552.
  8. Dharmawardhana P, Ren L, Amarasinghe V, Monaco M, Thomason J, Ravenscroft D, McCouch S, Ware D, Jaiswal P (2013). A genome scale metabolic network for rice and accompanying analysis of tryptophan, auxin and serotonin biosynthesis regulation under biotic stress. Rice 6:1-15.
  9. Monaco MK, Sen T, Dharmawardhana P, Ren L, Schaeffer M, Naithani S, Amarasinghe V, Thomason J, Harper L, Gardiner J, Cannon EKS, Lawrence CJ, Ware D, and Jaiswal P. 2012. Maize metabolic network construction and transcriptome analysis. The Plant Genome 6:1-12.
  10. Dugas DV, Monaco MK, Olsen A, Klein RR, Kumari S, Ware D and Klein PE. 2011. Functional annotation of the transcriptome of Sorghum bicolor in response to osmotic stress and abscisic acid. BMC Genomics. 12:514-535.
  11. Florez JC, Price AL, Yu F, Riba L, Bedoya G, Saxena R, Tello-Ruiz M, Aguilar-Salinas CA, Canizales S, Tusié-Luna T, Ruiz-Linares A, Reich D. 2009. Strong association of socioeconomic status with genetic ancestry in Latinos: implications for admixture studies of type 2 diabetes. Diabetologia. 52(8):1528-36.
  12. Prokopenko I, Zeggini E, Hanson RL, Mitchell BD, Rayner NW, Akan P, Baier L, Das SK, Elliott KS, Fu M, Frayling TM, Groves CJ, William RG, Scott LJ, Voight BF, Hattersley AT, Hu C, Morris AD, Ng M, Palmer CNA, Tello-Ruiz M, Vaxillaire M, Wang C, Stein L, Chan J, Jia W, Froguel P, Elbein SC, Deloukas P, Bogardus C, Shuldiner AR, McCarthy MI for the International Type 2 Diabetes 1q consortium. 2009. Linkage disequilibrium mapping of the replicated type 2 diabetes linkage signal on chromosome 1q. Diabetes. 58(7):1704-9. 
  13. Labbé C, Goyette P, Lefebvre C, Stevens C, Green T, Tello-Ruiz MK, Cao Z, Landry AL, Stempak J, Annese V, Latiano A, Brant SR, Duerr RH, Taylor KD, Cho JH, Steinhart AH, Daly MJ, Silverberg MS, Xavier RJ, Rioux JD. 2008. MAST3: a novel IBD risk factor that modulates TLR4 signaling. Genes Immun. 9(7):602-12.
  14. International HapMap Consortium. 2007. A second generation human haplotype map of over 3.1 million SNPs. Nature. 449(7164):851-61. 
  15. Sabeti PC, Varilly P, Fry B, Lohmueller J, Hostetter E, Cotsapas C, Xie X, Byrne EH, McCarroll SA, Gaudet R, Schaffner SF, Lander ES; International HapMap Consortium. 2007. Genome-wide detection and characterization of positive selection in human populations. Nature. 449(7164):913-8.
  16. Price AL, Patterson N, Yu F, Cox DR, Waliszewska A, McDonald GJ, Tandon A, Schirmer C, Neubauer J, Bedoya G, Duque C, Villegas A, Bortolini MC, Salzano FM, Gallo C, Mazzotti G, Tello-Ruiz M, Riba L, Aguilar-Salinas CA, Canizales-Quinteros S, Menjivar M, Klitz W, Henderson B, Haiman CA, Winkler C, Tusié-Luna T, Ruiz-Linares A, Reich D. 2007. A genomewide admixture map for Latino populations. Am J Hum Genet. 80(6):1024-36.
  17. Tello-Ruiz MK, Curley C, Miller K, Giallourakis C, Kirby A, Bitton A, Cohen A, Langelier D, Wild G, Daly MJ, and Rioux JD. 2006. Haplotype-based association analysis of 56 functional candidate genes in the IBD6 locus on chromosome 19. Eur J Hum Genet. 14(6):780-90.
  18. Harris TW, Chen N, Cunningham F, Tello-Ruiz M, Antoshechkin I, Bastiani C, Bieri T, Blasiar D, Bradnam K, Chan J, Chen CK, Chen WJ, Davis P, Kenny E, Kishore R, Lawson D, Lee R, Muller HM, Nakamura C, Ozersky P, Petcherski A, Rogers A, Sabo A, Schwarz EM, Van Auken K, Wang Q, Durbin R, Spieth J, Sternberg PW, Stein LD.  2004. WormBase: a multi-species resource for nematode biology and genomics. Nucleic Acids Res. 32:D411-7.
  19. Drier EA, Tello MK, Cowan M, Wu P, Blace N, Sacktor TC, Yin JC. 2002. Memory enhancement and formation by atypical PKM activity in Drosophila melanogaster. Nature Neurosci. 5(4):316-24.
  20. Hendricks JC, Williams JA, Panckeri K, Kirk D, Tello M, Yin JC, Sehgal A. 2001. A non-circadian role for cAMP signaling and CREB activity in Drosophila rest homeostasis. Nature Neurosci. 4(11):1108-15.
  21.   Hurtado L, Castrezana S, Mateos M, McLaurin D, Tello MK, Campoy J and Markow T. 1996. Developmental stability and environmental stress in natural populations of Drosophila pachea.  Ecotoxicology. 6, 233-238.








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